Matefin/SUN-1 Phosphorylation on Serine 43 Is Mediated by CDK-1 and Required for Its Localization to Centrosomes and Normal Mitosis in C. elegans Embryos

Matefin/SUN-1 Phosphorylation on Serine 43 Is Mediated by CDK-1 and Required for Its Localization to Centrosomes and Normal Mitosis in C. elegans Embryos

Matefin/SUN-1 is an evolutionary conserved C. elegans inner nuclear membrane SUN-domain protein. By creating a bridge with the KASH-domain protein ZYG-12, it connects the nucleus to cytoplasmic filaments and organelles. Matefin/SUN-1 is expressed in the germline where it undergoes specific phosphory...

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Bibliographic Details
Main Authors: Noam Zuela, Yosef Gruenbaum
Format: Article
Language:English
Published: MDPI AG 2016-02-01
Series:Cells
Subjects:
C. elegans
centrosome
LINC complex
mitosis
meiosis
SUN-domain
Online Access:http://www.mdpi.com/2073-4409/5/1/8

Internet

http://www.mdpi.com/2073-4409/5/1/8

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