Rapid Purification and Procoagulant and Platelet Aggregating Activities of Rhombeobin: A Thrombin-Like/Gyroxin-Like Enzyme from Lachesis muta rhombeata Snake Venom

Rapid Purification and Procoagulant and Platelet Aggregating Activities of Rhombeobin: A Thrombin-Like/Gyroxin-Like Enzyme from Lachesis muta rhombeata Snake Venom

We report a rapid purification method using one-step chromatography of SVSP Rhombeobin (LMR-47) from Lachesis muta rhombeata venom and its procoagulant activities and effects on platelet aggregation. The venom was fractionated by a single chromatographic step in RP-HPLC on a C8 Discovery BIO Wide Po...

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Bibliographic Details
Main Authors: Frank Denis Torres-Huaco, Cláudio C. Werneck, Cristina Pontes Vicente, Talita Vassequi-Silva, Ana Cláudia Coelho Nery-Diez, Camila B. Mendes, Edson Antunes, Sérgio Marangoni, Daniela C. S. Damico
Format: Article
Language:English
Published: Hindawi Limited 2013-01-01
Series:BioMed Research International
Online Access:http://dx.doi.org/10.1155/2013/903292

Internet

http://dx.doi.org/10.1155/2013/903292

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