MIR155 Regulation of Ubiquilin1 and Ubiquilin2: Implications in Cellular Protection and Tumorigenesis

Ubiquilin (UBQLN) proteins are adaptors thought to link ubiquitinated proteins to the proteasome. However, our lab has recently reported a previously unappreciated role for loss of UBQLN in lung cancer progression. In fact, UBQLN genes are lost in over 50% of lung cancer samples examined. However, a...

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Bibliographic Details
Main Authors: Sanjay Yadav, Nishant Singh, Parag P. Shah, David A. Rowbotham, Danial Malik, Ankita Srivastav, Jai Shankar, Wan L. Lam, William W. Lockwood, Levi J. Beverly
Format: Article
Language:English
Published: Elsevier 2017-04-01
Series:Neoplasia: An International Journal for Oncology Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558617300027