Yeast microcapsule-mediated oral delivery of IL-1β shRNA for post-traumatic osteoarthritis therapy

Yeast microcapsule-mediated oral delivery of IL-1β shRNA for post-traumatic osteoarthritis therapy

Post-traumatic osteoarthritis is a prevalent debilitating joint disease. However, there is no FDA-approved disease-modifying osteoarthritis drug currently. Gene therapy can improve disease progression but lacks an effective delivery system. Here, we constructed an oral drug delivery system by non-vi...

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Bibliographic Details
Main Authors: Long Zhang, Hang Peng, Meng Feng, Wan Zhang, Yankun Li
Format: Article
Language:English
Published: Elsevier 2021-03-01
Series:Molecular Therapy: Nucleic Acids
Subjects:
post-traumatic osteoarthritis
gene therapy
oral administration
yeast microcapsule
Online Access:http://www.sciencedirect.com/science/article/pii/S2162253120303620

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http://www.sciencedirect.com/science/article/pii/S2162253120303620

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