A Facile One-Pot Process for the Formation of Hindered Tertiary Amines

A Facile One-Pot Process for the Formation of Hindered Tertiary Amines

A simple and convenient method was developed for the preparation of hindered tertiary amines via direct reductive amination of ketones with secondary aryl amines, using trichlorosilane as reducing agent and tetramethylethylenediamine (TMEDA) as organic Lewis base activator. A broad range of ketones...

Full description

Bibliographic Details
Main Authors: Jian Sun, Chao Wang, Yu Zhang, Zhouyu Wang, Dong Pei
Format: Article
Language:English
Published: MDPI AG 2012-05-01
Series:Molecules
Subjects:
reductive amination
tertiary amine
Lewis base
trichlorosilane
ketone
Online Access:http://www.mdpi.com/1420-3049/17/5/5151

Internet

http://www.mdpi.com/1420-3049/17/5/5151

Similar Items