Analysis of G-quadruplexes upstream of herpesvirus miRNAs: evidence of G-quadruplex mediated regulation of KSHV miR-K12–1-9,11 cluster and HCMV miR-US33

Analysis of G-quadruplexes upstream of herpesvirus miRNAs: evidence of G-quadruplex mediated regulation of KSHV miR-K12–1-9,11 cluster and HCMV miR-US33

Abstract Background G-quadruplexes regulate gene expression, recombination, packaging and latency in herpesviruses. Herpesvirus-encoded miRNAs have been linked to important biological functions. The presence and the biological role of G-quadruplexes have not been studied in the regulatory regions of...

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Bibliographic Details
Main Authors: Shivani Kumar, Divya Choudhary, Anupam Patra, Neel Sarovar Bhavesh, Perumal Vivekanandan
Format: Article
Language:English
Published: BMC 2020-09-01
Series:BMC Molecular and Cell Biology
Subjects:
Herpesvirus
G-quadruplexes
MiRNA
Kaposi's sarcoma-associated Herpesvirus
Human Cytomegalovirus
Online Access:http://link.springer.com/article/10.1186/s12860-020-00306-w

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http://link.springer.com/article/10.1186/s12860-020-00306-w

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