Dispersible hydrogel force sensors reveal patterns of solid mechanical stress in multicellular spheroid cultures

Dispersible hydrogel force sensors reveal patterns of solid mechanical stress in multicellular spheroid cultures

Understanding how forces orchestrate tissue formation requires technologies to map internal tissue stress at cellular length scales. Here, authors develop ultrasoft sensors that visibly deform under cell-generated stress to capture patterns of internal stress development during multicellular spheroi...

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Bibliographic Details
Main Authors: Wontae Lee, Nikita Kalashnikov, Stephanie Mok, Ruba Halaoui, Elena Kuzmin, Andrew J. Putnam, Shuichi Takayama, Morag Park, Luke McCaffrey, Ruogang Zhao, Richard L. Leask, Christopher Moraes
Format: Article
Language:English
Published: Nature Publishing Group 2019-01-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-018-07967-4

Internet

https://doi.org/10.1038/s41467-018-07967-4

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