A SOX9‐AS1/miR‐5590‐3p/SOX9 positive feedback loop drives tumor growth and metastasis in hepatocellular carcinoma through the Wnt/β‐catenin pathway

Hepatocellular carcinoma (HCC) is a prevalent solid tumor with a high global death rate. SRY box 9 (SOX9) has been reported as an oncogene in HCC by several studies, but the underlying mechanism remains largely unexplored. Here, we confirmed upregulation of SOX9 in HCC tissues and cell lines and val...

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Bibliographic Details
Main Authors: Wei Zhang, Yanhui Wu, Bingwu Hou, Yadong Wang, Dongfeng Deng, Zhihao Fu, Zongquan Xu
Format: Article
Language:English
Published: Wiley 2019-10-01
Series:Molecular Oncology
Subjects:
Online Access:https://doi.org/10.1002/1878-0261.12560