Pancreatic cancer prognosis is predicted by an ATAC-array technology for assessing chromatin accessibility

ATAC-seq allows for the investigation of chromatin accessibility, a feature which can have important implications for gene regulation. Here the authors present ATAC-array to assess accessibility in human tumours and based on this predict disease prognosis.

Bibliographic Details
Main Authors: S. Dhara, S. Chhangawala, H. Chintalapudi, G. Askan, V. Aveson, A. L. Massa, L. Zhang, D. Torres, A. P. Makohon-Moore, N. Lecomte, J. P. Melchor, J. Bermeo, A. Cardenas, S. Sinha, D. Glassman, R. Nicolle, R. Moffitt, K. H. Yu, S. Leppanen, S. Laderman, B. Curry, J. Gui, V. P. Balachandran, C. Iacobuzio-Donahue, R. Chandwani, C. S. Leslie, S. D. Leach
Format: Article
Language:English
Published: Nature Publishing Group 2021-05-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-021-23237-2