Increased Oxidative Stress Underlies Abnormal Pain Threshold in a Normoglycemic Japanese Population

Increased Oxidative Stress Underlies Abnormal Pain Threshold in a Normoglycemic Japanese Population

Normal-high HbA1c levels are a risk factor for attenuated pain sensation in normoglycemic subjects. It is unclear, however, what mechanisms underlie the pathogenesis of attenuated pain sensation in such a population. We, therefore, explored the relationship between oxidative stress (OS) and pain sen...

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Bibliographic Details
Main Authors: Sho Osonoi, Hiroki Mizukami, Chieko Itabashi, Kanichiro Wada, Kazuhiro Kudoh, Akiko Igawa, Saori Ogasawara, Yasuyuki Ishibashi, Makoto Daimon, Soroku Yagihashi, Shigeyuki Nakaji
Format: Article
Language:English
Published: MDPI AG 2020-11-01
Series:International Journal of Molecular Sciences
Subjects:
elevated pain threshold
diabetic polyneuropathy
oxidative stress
8-hydroxy-2′-deoxyguanosine
normal-high HbA1c
inflammation
Online Access:https://www.mdpi.com/1422-0067/21/21/8306

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https://www.mdpi.com/1422-0067/21/21/8306

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