IL-13 induces a bronchial epithelial phenotype that is profibrotic

<p>Abstract</p> <p>Background</p> <p>Inflammatory cytokines (e.g. IL-13) and mechanical perturbations (e.g. scrape injury) to the epithelium release profibrotic factors such as TGF-β<sub>2</sub>, which may, in turn, stimulate subepithelial fibrosis in asthma...

Full description

Bibliographic Details
Main Authors: Dinh Bao T, Raub Christopher B, Mih Justin D, Malavia Nikita K, George Steven C
Format: Article
Language:English
Published: BMC 2008-03-01
Series:Respiratory Research
Online Access:http://respiratory-research.com/content/9/1/27