Mifepristone Increases Life Span of Virgin Female Drosophila on Regular and High-fat Diet Without Reducing Food Intake

Mifepristone Increases Life Span of Virgin Female Drosophila on Regular and High-fat Diet Without Reducing Food Intake

Background: The synthetic steroid mifepristone is reported to have anti-obesity and anti-diabetic effects in mammals on normal and high-fat diets (HFD). We previously reported that mifepristone blocks the negative effect on life span caused by mating in female Drosophila melanogaster.Methods: Here w...

Full description

Bibliographic Details
Main Authors: Gary N. Landis, Tyler A. U. Hilsabeck, Hans S. Bell, Tal Ronnen-Oron, Lu Wang, Devon V. Doherty, Felicia I. Tejawinata, Katherine Erickson, William Vu, Daniel E. L. Promislow, Pankaj Kapahi, John Tower
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-09-01
Series:Frontiers in Genetics
Subjects:
aging
mifepristone
life span
high-fat diet
steroid
tryptophan
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2021.751647/full

Internet

https://www.frontiersin.org/articles/10.3389/fgene.2021.751647/full

Similar Items