Exosomal microRNA-15a from mesenchymal stem cells impedes hepatocellular carcinoma progression via downregulation of SALL4

Exosomal microRNA-15a from mesenchymal stem cells impedes hepatocellular carcinoma progression via downregulation of SALL4

Abstract Hepatocellular carcinoma (HCC) is a heterogeneous tumor with an increased incidence worldwide accompanied by high mortality and dismal prognosis. Emerging evidence indicates that mesenchymal stem cells (MSCs)-derived exosomes possess protective effects against various human diseases by tran...

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Main Authors: Yu-Shui Ma, Ji-Bin Liu, Lan Lin, Hui Zhang, Jian-Jun Wu, Yi Shi, Cheng-You Jia, Dan-Dan Zhang, Fei Yu, Hui-Min Wang, Yu-Zhen Yin, Xiao-Hui Jiang, Pei-Yao Wang, Lin-Lin Tian, Ping-Sheng Cao, Xu-Ming Wu, Hai-Min Lu, Li-Peng Gu, Jia-Jia Zhang, Gu-Jun Cong, Pei Luo, Xiao-Ming Zhong, Bo Cai, Min-Xin Shi, Su-Qing Zhang, Liu Li, Wen-Jie Zhang, Yu Liu, Zhi-Zhen Li, Ting-Miao Wu, Zhi-Jun Wu, Gao-Ren Wang, Zhong-Wei Lv, Chang-Chun Ling, Kai-Jian Chu, Da Fu
Format: Article
Language:English
Published: Nature Publishing Group 2021-08-01
Series:Cell Death Discovery
Online Access:https://doi.org/10.1038/s41420-021-00611-z

Internet

https://doi.org/10.1038/s41420-021-00611-z

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