Recommendations for cerebrospinal fluid collection for the analysis by ELISA of neurogranin trunc P75, α-synuclein, and total tau in combination with Aβ(1–42)/Aβ(1–40)

Recommendations for cerebrospinal fluid collection for the analysis by ELISA of neurogranin trunc P75, α-synuclein, and total tau in combination with Aβ(1–42)/Aβ(1–40)

Abstract Background The pathophysiology of neurodegeneration is complex. Its diagnosis requires an early identification of sequential changes in several hallmarks in the brains of affected subjects. The presence of brain pathology can be visualized in the cerebrospinal fluid (CSF) by protein profili...

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Bibliographic Details
Main Authors: Hugo Vanderstichele, Leentje Demeyer, Shorena Janelidze, Els Coart, Erik Stoops, Kimberley Mauroo, Victor Herbst, Cindy François, Oskar Hansson
Format: Article
Language:English
Published: BMC 2017-06-01
Series:Alzheimer’s Research & Therapy
Subjects:
CSF
Collection
Standardization
Neurogranin
Synuclein
Tau
Online Access:http://link.springer.com/article/10.1186/s13195-017-0265-7

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http://link.springer.com/article/10.1186/s13195-017-0265-7

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