Amentoflavone as an Ally in the Treatment of Cutaneous Leishmaniasis: Analysis of Its Antioxidant/Prooxidant Mechanisms

Amentoflavone as an Ally in the Treatment of Cutaneous Leishmaniasis: Analysis of Its Antioxidant/Prooxidant Mechanisms

Treatment of leishmaniasis is a challenging subject. Although available, chemotherapy is limited, presenting toxicity and adverse effects. New drugs with antileishmanial activity are being investigated, such as antiparasitic compounds derived from plants. In this work, we investigated the antileishm...

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Bibliographic Details
Main Authors: Yasmin Silva Rizk, Sandy Santos-Pereira, Luiza Gervazoni, Daiana de Jesus Hardoim, Flávia de Oliveira Cardoso, Celeste da Silva Freitas de Souza, Marcelo Pelajo-Machado, Carlos Alexandre Carollo, Carla Cardozo Pinto de Arruda, Elmo Eduardo Almeida-Amaral, Tânia Zaverucha-do-Valle, Kátia da Silva Calabrese
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-02-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
amentoflavone
biflavonoid
prooxidant
antileishmanial activity
intralesional treatment
cutaneous leishmaniasis
Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2021.615814/full

Internet

https://www.frontiersin.org/articles/10.3389/fcimb.2021.615814/full

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