A dual-therapy approach for the treatment of biofilm-mediated Salmonella gallbladder carriage.

Asymptomatic carriage of Salmonella Typhi continues to facilitate the transmission of typhoid fever, resulting in 14 million new infections and 136,000 fatalities each year. Asymptomatic chronic carriage of S. Typhi is facilitated by the formation of biofilms on gallstones that protect the bacteria...

Full description

Bibliographic Details
Main Authors: Jenna L Sandala, Bradley W Eichar, Laura G Kuo, Mark M Hahn, Akash K Basak, William M Huggins, Katherine Woolard, Christian Melander, John S Gunn
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-12-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1009192