DNX-2401, an Oncolytic Virus, for the Treatment of Newly Diagnosed Diffuse Intrinsic Pontine Gliomas: A Case Report

DNX-2401, an Oncolytic Virus, for the Treatment of Newly Diagnosed Diffuse Intrinsic Pontine Gliomas: A Case Report

Diffuse intrinsic pontine gliomas (DIPGs) are aggressive glial brain tumors that primarily affect children, for which there is no curative treatment. Median overall survival is only one year. Currently, the scientific focus is on expanding the knowledge base of the molecular biology of DIPG, and ide...

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Bibliographic Details
Main Authors: Sonia Tejada, Ricardo Díez-Valle, Pablo D. Domínguez, Ana Patiño-García, Marisol González-Huarriz, Juan Fueyo, Cande Gomez-Manzano, Miguel Angel Idoate, Joanna Peterkin, Marta M. Alonso
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-03-01
Series:Frontiers in Oncology
Subjects:
diffuse intrinsic pontine gliomas
phase I clinical trial
oncolytic virus
delta-24-RGD
DNX-2401
intratumoral
Online Access:http://journal.frontiersin.org/article/10.3389/fonc.2018.00061/full

Internet

http://journal.frontiersin.org/article/10.3389/fonc.2018.00061/full

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