Transglutaminase 3 Reduces the Severity of Psoriasis in Imiquimod-Treated Mouse Skin

Transglutaminase 3 Reduces the Severity of Psoriasis in Imiquimod-Treated Mouse Skin

Four transglutaminase (TG) isoforms have been detected in epidermal keratinocytes: TG1, TG2, TG3, and TG5. Except for TG1 and TG3, their contribution to keratinocyte development and structure remains undefined. In this paper, we focused on the roles of TG2 and TG3 in imiquimod-induced psoriasis in m...

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Bibliographic Details
Main Authors: Maria Cristina Piro, Alessandra Ventura, Artem Smirnov, Andrea Saggini, Anna Maria Lena, Alessandro Mauriello, Luca Bianchi, Gerry Melino, Eleonora Candi
Format: Article
Language:English
Published: MDPI AG 2020-02-01
Series:International Journal of Molecular Sciences
Subjects:
transglutaminase 2
transglutaminase 3
psoriasis
imiquimod
inflammation
skin
tg3ko
tg2ko
Online Access:https://www.mdpi.com/1422-0067/21/5/1566

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https://www.mdpi.com/1422-0067/21/5/1566

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