Morphology and Progression in Primary Varicose Vein Disorder Due to 677C>T and 1298A>C Variants of MTHFR

Background: Clinical assessment and prognostic stratification of primary varicose veins have remained controversial and the molecular pathogenesis is unknown. Previous data have suggested a contribution of the MTHFR (methylenetetrahydrofolate reductase) polymorphism c.677C>T. Methods: We collecte...

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Bibliographic Details
Main Authors: Christoph Wilmanns, Alexis Cooper, Leesa Wockner, Sotirios Katsandris, Nadine Glaser, Alexander Meyer, Oliver Bartsch, Harald Binder, Paul Karl Walter, Ulrich Zechner
Format: Article
Language:English
Published: Elsevier 2015-02-01
Series:EBioMedicine
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396415000298