Burkholderia pseudomallei-loaded cells act as a Trojan horse to invade the brain during endotoxemia

Abstract Neurologic melioidosis occurs in both human and animals; however, the mechanism by which the pathogen Burkholderia pseudomallei invades the central nervous system (CNS) remains unclear. B. pseudomallei-loaded Ly6C cells have been suggested as a putative portal; however, during melioidosis,...

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Bibliographic Details
Main Authors: Pei-Tan Hsueh, Hsi-Hsun Lin, Chiu-Lin Liu, Wei-Fen Ni, Ya-Lei Chen, Yao-Shen Chen
Format: Article
Language:English
Published: Nature Publishing Group 2018-09-01
Series:Scientific Reports
Subjects:
Online Access:https://doi.org/10.1038/s41598-018-31778-8