Matrix metalloproteinase-20 over-expression is detrimental to enamel development: a Mus musculus model.

Matrix metalloproteinase-20 (Mmp20) ablated mice have enamel that is thin and soft with an abnormal rod pattern that abrades from the underlying dentin. We asked if introduction of transgenes expressing Mmp20 would revert this Mmp20 null phenotype back to normal. Unexpectedly, for transgenes express...

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Bibliographic Details
Main Authors: Masashi Shin, Yuanyuan Hu, Coralee E Tye, Xiaomu Guan, Craig C Deagle, Jerry V Antone, Charles E Smith, James P Simmer, John D Bartlett
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3900650?pdf=render