Glutathione S-transferase A2 promotes hepatocellular carcinoma recurrence after liver transplantation through modulating reactive oxygen species metabolism

Abstract Hepatocellular carcinoma (HCC) recurrence after liver transplantation remains a significant clinical problem. Ischemia-reperfusion injury (IRI) occurred inevitably at the early phase after liver transplantation (LT) spawns a significant risk of HCC recurrence. However, their linkage and IRI...

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Bibliographic Details
Main Authors: Kevin Tak-Pan Ng, Oscar Wai-Ho Yeung, Yin Fan Lam, Jiang Liu, Hui Liu, Li Pang, Xin Xiang Yang, Jiye Zhu, Weiyi Zhang, Matthew Y. H. Lau, Wen Qi Qiu, Hoi Chung Shiu, Man Kit Lai, Chung Mau Lo, Kwan Man
Format: Article
Language:English
Published: Nature Publishing Group 2021-07-01
Series:Cell Death Discovery
Online Access:https://doi.org/10.1038/s41420-021-00569-y