Molecular dynamics studies of the nucleoprotein of influenza A virus: role of the protein flexibility in RNA binding.

The influenza viruses contain a segmented, negative stranded RNA genome. Each RNA segment is covered by multiple copies of the nucleoprotein (NP). X-ray structures have shown that NP contains well-structured domains juxtaposed with regions of missing electron densities corresponding to loops. In thi...

Full description

Bibliographic Details
Main Authors: Bogdan Tarus, Christophe Chevalier, Charles-Adrien Richard, Bernard Delmas, Carmelo Di Primo, Anny Slama-Schwok
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3260217?pdf=render