Endoplasmic Reticulum Detergent-Resistant Membranes Accommodate Hepatitis C Virus Proteins for Viral Assembly

Endoplasmic Reticulum Detergent-Resistant Membranes Accommodate Hepatitis C Virus Proteins for Viral Assembly

During Hepatitis C virus (HCV) morphogenesis, the non-structural protein 2 (NS2) brings the envelope proteins 1 and 2 (E1, E2), NS3, and NS5A together to form a complex at the endoplasmic reticulum (ER) membrane, initiating HCV assembly. The nature of the interactions in this complex is unclear, but...

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Bibliographic Details
Main Authors: Audrey Boyer, Julie Dreneau, Amélie Dumans, Julien Burlaud-Gaillard, Anne Bull-Maurer, Philippe Roingeard, Jean-Christophe Meunier
Format: Article
Language:English
Published: MDPI AG 2019-05-01
Series:Cells
Subjects:
HCV
morphogenesis
detergent resistant membrane
Apolipoprotein E (ApoE)
NS2
Online Access:https://www.mdpi.com/2073-4409/8/5/487

Internet

https://www.mdpi.com/2073-4409/8/5/487

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