WhiB4 Regulates the PE/PPE Gene Family and is Essential for Virulence of Mycobacterium marinum

Abstract During the course of infection, pathogenic mycobacteria including Mycobacterium tuberculosis (M. tb) encounter host environments of variable oxygen tension, ranging from the hypoxic center of granulomas to the most oxygenated region in the lung cavities. Mycobacterial responses to changes o...

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Bibliographic Details
Main Authors: Jing Wu, Huan-wei Ru, Zhi-hao Xiang, Jun Jiang, Yu-chen Wang, Lu Zhang, Jun Liu
Format: Article
Language:English
Published: Nature Publishing Group 2017-06-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-03020-4