P38 MAP kinase inhibitors as potential therapeutics for the treatment of joint degeneration and pain associated with osteoarthritis

<p>Abstract</p> <p>Background</p> <p>Evaluate the potential role of p38 inhibitors for the treatment of osteoarthritis using an animal model of joint degeneration (iodoacetate-induced arthritis) and a pain model (Hargraeves assay).</p> <p>Methods</p> &...

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Bibliographic Details
Main Authors: Taiwo Yetunde O, Buchalova Maria, Hsieh Lily, Hookfin Erin B, Heitmeyer Sandra A, Brown Kimberly K, Janusz Michael J
Format: Article
Language:English
Published: BMC 2008-12-01
Series:Journal of Inflammation
Online Access:http://www.journal-inflammation.com/content/5/1/22