GRK2 Constitutively Governs Peripheral Delta Opioid Receptor Activity

Opioids remain the standard for analgesic care; however, adverse effects of systemic treatments contraindicate long-term administration. While most clinical opioids target mu opioid receptors (MOR), those that target the delta class (DOR) also demonstrate analgesic efficacy. Furthermore, peripherall...

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Bibliographic Details
Main Authors: Allison Doyle Brackley, Ruben Gomez, Armen N. Akopian, Michael A. Henry, Nathaniel A. Jeske
Format: Article
Language:English
Published: Elsevier 2016-09-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124716310300