Variation of 46 Innate Immune Genes Evaluated for their Contribution in Pneumococcal Meningitis Susceptibility and Outcome

Variation of 46 Innate Immune Genes Evaluated for their Contribution in Pneumococcal Meningitis Susceptibility and Outcome

Pneumococcal meningitis is the most common and severe form of bacterial meningitis. Early recognition of the pathogen and subsequent innate immune response play a vital role in disease susceptibility and outcome. Genetic variations in innate immune genes can alter the immune response and influence s...

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Bibliographic Details
Main Authors: Bart Ferwerda, Mercedes Valls Serón, Aldo Jongejan, Aeilko H. Zwinderman, Madelijn Geldhoff, Arie van der Ende, Frank Baas, Matthijs C. Brouwer, Diederik van de Beek
Format: Article
Language:English
Published: Elsevier 2016-08-01
Series:EBioMedicine
Subjects:
Innate immunity
Pneumococcal meningitis
IRAK4
NOD2
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396416303164

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http://www.sciencedirect.com/science/article/pii/S2352396416303164

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