pCRP-mCRP Dissociation Mechanisms as Potential Targets for the Development of Small-Molecule Anti-Inflammatory Chemotherapeutics

pCRP-mCRP Dissociation Mechanisms as Potential Targets for the Development of Small-Molecule Anti-Inflammatory Chemotherapeutics

Circulating C-reactive protein (CRP) is a key acute-phase protein and one of the main clinical biomarkers for inflammation and infection. CRP is an important upstream mediator of inflammation and is associated with the onset of a number of important disease states including cardiovascular disease an...

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Bibliographic Details
Main Authors: Vittorio Caprio, Lina Badimon, Mario Di Napoli, Wen-Hui Fang, Glenn R. Ferris, Baoqiang Guo, Rocco S. Iemma, Donghui Liu, Yasmin Zeinolabediny, Mark Slevin
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-05-01
Series:Frontiers in Immunology
Subjects:
CRP
inflammation
chemotherapy
phospholipid
phospholipase
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2018.01089/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2018.01089/full

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