Exposure to Tissue Culture Conditions Can Adversely Affect Myoblast Behavior in Vivo in Whole Muscle Grafts: Implications for Myoblast Transfer Therapy

The effects of tissue culture conditions on the viability of myoblasts in whole muscles transplanted in vivo were investigated. Whole male (SJL/J) donor muscles were exposed to various tissue culture reagents and proteolytic enzymes, and allografted into female (SJL/J) host mice. Desmin immunohistoc...

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Bibliographic Details
Main Authors: Gayle M. Smythe, Miranda D. Grounds
Format: Article
Language:English
Published: SAGE Publishing 2000-05-01
Series:Cell Transplantation
Online Access:https://doi.org/10.1177/096368970000900309