Application of Antibody-Mediated Therapy for Treatment and Prevention of Clostridium difficile Infection

Clostridium difficile causes antibiotic- and healthcare-associated diarrhea, which is characterized by a high mortality rate (5–15%) and high recurrence rate of 20% or more. Therapeutic alternatives to antibiotics are urgently needed to improve the overall cure rate. Among these, therapeutic antibod...

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Bibliographic Details
Main Authors: Beatrix Förster, Pui Khi Chung, Monique J. T. Crobach, Ed J. Kuijper
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-06-01
Series:Frontiers in Microbiology
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2018.01382/full