A novel strategy to improve antigen presentation for active immunotherapy in cancer. Fusion of the human papillomavirus type 16 E7 antigen to a cell penetrating peptide

Facilitating the delivery of exogenous antigens to antigen-presenting cells, ensuing processing and presentation via the major histocompatibility complex class I and induction of an effective immune response are fundamental for an effective therapeutic cancer vaccine. In this regard, we propose the...

Full description

Bibliographic Details
Main Authors: Milaid Granadillo, Isis Torrens, Maribel Guerra, Aileen Batte, Yordanka Soria, Osmani Mendoza, Aracelys Blanco, Alexis Musacchio, Victoria M Lugo
Format: Article
Language:English
Published: Elfos Scientiae
Series:Biotecnología Aplicada
Subjects:
e7
Online Access:http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S1027-28522012000300007&lng=en&tlng=en