A novel strategy to improve antigen presentation for active immunotherapy in cancer. Fusion of the human papillomavirus type 16 E7 antigen to a cell penetrating peptide
Facilitating the delivery of exogenous antigens to antigen-presenting cells, ensuing processing and presentation via the major histocompatibility complex class I and induction of an effective immune response are fundamental for an effective therapeutic cancer vaccine. In this regard, we propose the...
Main Authors: | , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Elfos Scientiae
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Series: | Biotecnología Aplicada |
Subjects: | |
Online Access: | http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S1027-28522012000300007&lng=en&tlng=en |