Prolonged systemic inflammation persistently modifies synaptic plasticity in the hippocampus: modulation by the stress hormones.

Transient systemic inflammation has been shown to cause altered behavior both in humans and in laboratory animals through activation of microglia and heightened level of cytokines detected in the brain and in the body. Furthermore, both activated microglia and the increased cytokines level have been...

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Bibliographic Details
Main Authors: Nicola eMaggio, Efrat eShavit-Stein, Amir eDori, Ilan eBlatt, Joab eChapman
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-12-01
Series:Frontiers in Molecular Neuroscience
Subjects:
LTP
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnmol.2013.00046/full