Comparison of genetic and epigenetic alterations of primary tumors and matched plasma samples in patients with colorectal cancer.

Comparison of genetic and epigenetic alterations of primary tumors and matched plasma samples in patients with colorectal cancer.

BACKGROUND:Although recent advances in circulating DNA analysis allow the prediction of tumor genomes by noninvasive means, some challenges remain, which limit the widespread introduction of cfDNA in cancer diagnostics. We analyzed the status of the two best characterized colorectal cancer (CRC) gen...

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Main Authors: Elisa Danese, Anna Maria Minicozzi, Marco Benati, Martina Montagnana, Elisa Paviati, Gian Luca Salvagno, Gabriel Lima-Oliveira, Milena Gusella, Felice Pasini, Giuseppe Lippi, Gian Cesare Guidi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4422441?pdf=render

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http://europepmc.org/articles/PMC4422441?pdf=render

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