Intranasal versus intratracheal exposure to lipopolysaccharides in a murine model of acute respiratory distress syndrome

Abstract Due to frequent and often severe lung affections caused by COVID-19, murine models of acute respiratory distress syndrome (ARDS) are increasingly used in experimental lung research. The one induced by a single lipopolysaccharide (LPS) exposure is practical. However, whether it is preferable...

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Bibliographic Details
Main Authors: Fatemeh Khadangi, Anne-Sophie Forgues, Sophie Tremblay-Pitre, Alexis Dufour-Mailhot, Cyndi Henry, Magali Boucher, Marie-Josée Beaulieu, Mathieu Morissette, Liah Fereydoonzad, David Brunet, Annette Robichaud, Ynuk Bossé
Format: Article
Language:English
Published: Nature Publishing Group 2021-04-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-87462-x