Dissecting Integrin Expression and Function on Memory B Cells in Mice and Humans in Autoimmunity

Dissecting Integrin Expression and Function on Memory B Cells in Mice and Humans in Autoimmunity

Immunological memory ensures life-long protection against previously encountered pathogens, and in mice and humans the spleen is an important reservoir for long-lived memory B cells (MBCs). It is well-established that integrins play several crucial roles in lymphocyte survival and trafficking, but t...

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Bibliographic Details
Main Authors: Alessandro Camponeschi, Natalija Gerasimcik, Ying Wang, Timothy Fredriksson, Dongfeng Chen, Chiara Farroni, Katrin Thorarinsdottir, Louise Sjökvist Ottsjö, Alaitz Aranburu, Susanna Cardell, Rita Carsetti, Inger Gjertsson, Inga-Lill Mårtensson, Ola Grimsholm
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-03-01
Series:Frontiers in Immunology
Subjects:
integrins
LFA-1
VLA-4
memory B cells
adhesion
spleen
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.00534/full

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https://www.frontiersin.org/article/10.3389/fimmu.2019.00534/full

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