Desynchronization of neocortical networks by asynchronous release of GABA at autaptic and synaptic contacts from fast-spiking interneurons.

Desynchronization of neocortical networks by asynchronous release of GABA at autaptic and synaptic contacts from fast-spiking interneurons.

Networks of specific inhibitory interneurons regulate principal cell firing in several forms of neocortical activity. Fast-spiking (FS) interneurons are potently self-inhibited by GABAergic autaptic transmission, allowing them to precisely control their own firing dynamics and timing. Here we show t...

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Bibliographic Details
Main Authors: Frédéric Manseau, Silvia Marinelli, Pablo Méndez, Beat Schwaller, David A Prince, John R Huguenard, Alberto Bacci
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-09-01
Series:PLoS Biology
Online Access:http://europepmc.org/articles/PMC2946936?pdf=render

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http://europepmc.org/articles/PMC2946936?pdf=render

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