Nanoparticle delivery of grape seed-derived proanthocyanidins to airway epithelial cells dampens oxidative stress and inflammation

Nanoparticle delivery of grape seed-derived proanthocyanidins to airway epithelial cells dampens oxidative stress and inflammation

Abstract Background Chronic respiratory diseases, whose one of the hallmarks is oxidative stress, are still incurable and need novel therapeutic tools and pharmaceutical agents. The phenolic compounds contained in grape are endowed with well-recognized anti-oxidant, anti-inflammatory, anti-cancer, a...

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Bibliographic Details
Main Authors: S. Castellani, A. Trapani, A. Spagnoletta, L. di Toma, T. Magrone, S. Di Gioia, D. Mandracchia, G. Trapani, E. Jirillo, M. Conese
Format: Article
Language:English
Published: BMC 2018-05-01
Series:Journal of Translational Medicine
Subjects:
Oxidative stress
NF-κB
Airway epithelial cells
Solid lipid nanoparticles
Uptake
Apoptosis
Online Access:http://link.springer.com/article/10.1186/s12967-018-1509-4

Internet

http://link.springer.com/article/10.1186/s12967-018-1509-4

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