Up-regulated miR-145 Expression Inhibits Porcine Preadipocytes Differentiation by Targeting IRS1

<p>Generally, most miRNAs that were up-regulated during differentiation promoted adipogenesis, but our research indicated that up-regulation of miR-145 in porcine preadipocytes did not promote but inhibit adipogenesis. In this study, miR-145 was significantly up-regulated during porcine dediff...

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Bibliographic Details
Main Author: Yunxue Guo, Yaosheng Chen, Yun Zhang, Yue Zhang, Luxi Chen, Delin Mo
Format: Article
Language:English
Published: Ivyspring International Publisher 2012-01-01
Series:International Journal of Biological Sciences
Online Access:http://www.biolsci.org/v08p1408.htm