Development of functional genomic tools in trematodes: RNA interference and luciferase reporter gene activity in Fasciola hepatica.

The growing availability of sequence information from diverse parasites through genomic and transcriptomic projects offer new opportunities for the identification of key mediators in the parasite-host interaction. Functional genomics approaches and methods for the manipulation of genes are essential...

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Bibliographic Details
Main Authors: Gabriel Rinaldi, Maria E Morales, Martín Cancela, Estela Castillo, Paul J Brindley, José F Tort
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-07-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC2440534?pdf=render