Fibroblast and lymphoblast gene expression profiles in schizophrenia: are non-neural cells informative?

Fibroblast and lymphoblast gene expression profiles in schizophrenia: are non-neural cells informative?

Lymphoblastoid cell lines (LCLs) and fibroblasts provide conveniently derived non-neuronal samples in which to investigate the aetiology of schizophrenia (SZ) using gene expression profiling. This assumes that heritable mechanisms associated with risk of SZ have systemic effects and result in change...

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Bibliographic Details
Main Authors: Nicholas A Matigian, Richard D McCurdy, François Féron, Christopher Perry, Heather Smith, Cheryl Filippich, Duncan McLean, John McGrath, Alan Mackay-Sim, Bryan Mowry, Nicholas K Hayward
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2398775?pdf=render

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http://europepmc.org/articles/PMC2398775?pdf=render

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