Allspice and Clove As Source of Triterpene Acids Activating the G Protein-Coupled Bile Acid Receptor TGR5

Allspice and Clove As Source of Triterpene Acids Activating the G Protein-Coupled Bile Acid Receptor TGR5

Worldwide, metabolic diseases such as obesity and type 2 diabetes have reached epidemic proportions. A major regulator of metabolic processes that gained interest in recent years is the bile acid receptor TGR5 (Takeda G protein-coupled receptor 5). This G protein-coupled membrane receptor can be fou...

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Bibliographic Details
Main Authors: Angela Ladurner, Martin Zehl, Ulrike Grienke, Christoph Hofstadler, Nadina Faur, Fátima C. Pereira, David Berry, Verena M. Dirsch, Judith M. Rollinger
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-07-01
Series:Frontiers in Pharmacology
Subjects:
TGR5
Syzygium aromaticum
Pimenta dioica
Kaempferia galanga
triterpene acids
Online Access:http://journal.frontiersin.org/article/10.3389/fphar.2017.00468/full

Internet

http://journal.frontiersin.org/article/10.3389/fphar.2017.00468/full

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