Myelodysplastic syndrome patients present more severe respiratory muscle impairment and reduced forced vital capacity: Is disordered inflammatory signaling the culprit?

BACKGROUND/OBJECTIVES:The ageing process is associated with gradual decline in respiratory system performance. Anemia is highly prevalent among older adults and usually associated with adverse outcomes. Myelodysplastic syndromes (MDS) are a heterogeneous group of hematologic malignancies with increa...

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Bibliographic Details
Main Authors: Bruno Memória Okubo, Anacélia Gomes de Matos, Howard Lopes Ribeiro Junior, Daniela de Paula Borges, Roberta Taiane Germano de Oliveira, Marilena Facundo de Castro, Manoel Ricardo Alves Martins, Romélia Pinheiro Gonçalves, Pedro Felipe Carvalhedo Bruin, Ronald Feitosa Pinheiro, Silvia Maria Meira Magalhães
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5587331?pdf=render