GeneSurrounder: network-based identification of disease genes in expression data

Abstract Background A key challenge of identifying disease–associated genes is analyzing transcriptomic data in the context of regulatory networks that control cellular processes in order to capture multi-gene interactions and yield mechanistically interpretable results. One existing category of ana...

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Bibliographic Details
Main Authors: Sahil D. Shah, Rosemary Braun
Format: Article
Language:English
Published: BMC 2019-05-01
Series:BMC Bioinformatics
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12859-019-2829-y