Role of PINCH and its partner tumor suppressor Rsu-1 in regulating liver size and tumorigenesis.

Role of PINCH and its partner tumor suppressor Rsu-1 in regulating liver size and tumorigenesis.

Particularly interesting new cysteine-histidine-rich protein (PINCH) protein is part of the ternary complex known as the IPP (integrin linked kinase (ILK)-PINCH-Parvin-α) complex. PINCH itself binds to ILK and to another protein known as Rsu-1 (Ras suppressor 1). We generated PINCH 1 and PINCH 2 Dou...

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Bibliographic Details
Main Authors: Shashikiran Donthamsetty, Vishakha S Bhave, Wendy M Mars, William C Bowen, Anne Orr, Meagan M Haynes, Chuanyue Wu, George K Michalopoulos
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3776730?pdf=render

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http://europepmc.org/articles/PMC3776730?pdf=render

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