Mosaic autosomal aneuploidies are detectable from single-cell RNAseq data

Mosaic autosomal aneuploidies are detectable from single-cell RNAseq data

Abstract Background Aneuploidies are copy number variants that affect entire chromosomes. They are seen commonly in cancer, embryonic stem cells, human embryos, and in various trisomic diseases. Aneuploidies frequently affect only a subset of cells in a sample; this is known as “mosaic” aneuploidy....

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Bibliographic Details
Main Authors: Jonathan A. Griffiths, Antonio Scialdone, John C. Marioni
Format: Article
Language:English
Published: BMC 2017-11-01
Series:BMC Genomics
Subjects:
Aneuploidy detection
Single-cell
Copy-number
RNAseq
Online Access:http://link.springer.com/article/10.1186/s12864-017-4253-x

Internet

http://link.springer.com/article/10.1186/s12864-017-4253-x

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