The Advent of CAR T-Cell Therapy for Lymphoproliferative Neoplasms: Integrating Research Into Clinical Practice

The Advent of CAR T-Cell Therapy for Lymphoproliferative Neoplasms: Integrating Research Into Clinical Practice

Research on CAR T cells has achieved enormous progress in recent years. After the impressive results obtained in relapsed and refractory B-cell acute lymphoblastic leukemia and aggressive B-cell lymphomas, two constructs, tisagenlecleucel and axicabtagene ciloleucel, were approved by FDA. The role o...

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Bibliographic Details
Main Authors: Marco Cerrano, Marco Ruella, Miguel-Angel Perales, Candida Vitale, Danilo Giuseppe Faraci, Luisa Giaccone, Marta Coscia, Molly Maloy, Miriam Sanchez-Escamilla, Hesham Elsabah, Afraa Fadul, Enrico Maffini, Gianfranco Pittari, Benedetto Bruno
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-05-01
Series:Frontiers in Immunology
Subjects:
CAR T cells
adoptive immunotherapy
cellular therapy
lymphoma
leukemia
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.00888/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2020.00888/full

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