Neutrophil extracellular trap (NET)-mediated killing of Pseudomonas aeruginosa: evidence of acquired resistance within the CF airway, independent of CFTR.

Neutrophil extracellular trap (NET)-mediated killing of Pseudomonas aeruginosa: evidence of acquired resistance within the CF airway, independent of CFTR.

The inability of neutrophils to eradicate Pseudomonas aeruginosa within the cystic fibrosis (CF) airway eventually results in chronic infection by the bacteria in nearly 80 percent of patients. Phagocytic killing of P. aeruginosa by CF neutrophils is impaired due to decreased cystic fibrosis transme...

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Bibliographic Details
Main Authors: Robert L Young, Kenneth C Malcolm, Jennifer E Kret, Silvia M Caceres, Katie R Poch, David P Nichols, Jennifer L Taylor-Cousar, Milene T Saavedra, Scott H Randell, Michael L Vasil, Jane L Burns, Samuel M Moskowitz, Jerry A Nick
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3164657?pdf=render

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http://europepmc.org/articles/PMC3164657?pdf=render

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