The PLAGL2/MYCN/miR-506-3p interplay regulates neuroblastoma cell fate and associates with neuroblastoma progression

The PLAGL2/MYCN/miR-506-3p interplay regulates neuroblastoma cell fate and associates with neuroblastoma progression

Abstract Background The oncogene MYCN is critical for tumorigenesis of several types of cancers including neuroblastoma. We previously reported that miR-506-3p repressed MYCN expression in neuroblastoma cells. However, the mechanism underlying such regulation was undetermined since there is no miR-5...

Full description

Bibliographic Details
Main Authors: Zhenze Zhao, Spencer D. Shelton, Alejandro Oviedo, Amy L. Baker, Collin P. Bryant, Soroush Omidvarnia, Liqin Du
Format: Article
Language:English
Published: BMC 2020-02-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
miR-506-3p
Neuroblastoma
PLAGL2
MYCN
Retinoic acid
Cell differentiation
Online Access:http://link.springer.com/article/10.1186/s13046-020-1531-2

Internet

http://link.springer.com/article/10.1186/s13046-020-1531-2

Similar Items