Single cell sequencing reveals gene expression signatures associated with bone marrow stromal cell subpopulations and time in culture

Single cell sequencing reveals gene expression signatures associated with bone marrow stromal cell subpopulations and time in culture

Abstract Background Bone marrow stromal cells (BMSCs) are a heterogeneous population that participates in wound healing, immune modulation and tissue regeneration. Next generation sequencing was used to analyze transcripts from single BMSCs in order to better characterize BMSC subpopulations. Method...

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Bibliographic Details
Main Authors: Shutong Liu, David F. Stroncek, Yingdong Zhao, Victoria Chen, Rongye Shi, Jinguo Chen, Jiaqiang Ren, Hui Liu, Hee Joon Bae, Steven L. Highfill, Ping Jin
Format: Article
Language:English
Published: BMC 2019-01-01
Series:Journal of Translational Medicine
Subjects:
Bone marrow stromal cells
Next generation sequencing
Single cell next generation sequencing
FGFR2
PLAT
Online Access:http://link.springer.com/article/10.1186/s12967-018-1766-2

Internet

http://link.springer.com/article/10.1186/s12967-018-1766-2

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